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IGF 1 (UKB data field 30770)

AGBL5 · rs116176426

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.059 higher (95% confidence interval 0.044-0.074); p = 4 × 10−15.

How common The C allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 2, band 2p23.3 — in an intron of AGBL5.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of IGF 1 (UKB data field 30770) — no copies of the reported risk allele.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IGF 1 (UKB data field 30770).
C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IGF 1 (UKB data field 30770) compared to the general population.
Source

Questions about rs116176426

What is rs116176426?

rs116176426 is a single position in the genome, in or near the AGBL5 gene. Published research associates it with igf 1 (ukb data field 30770). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116176426 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116176426 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IGF 1 (UKB data field 30770) (rs116176426). MyGeneLog™. https://www.mygenelog.com/variants/rs116176426

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