Standard

Obstructive sleep apnea trait (percentage sleep with oxyhemoglobin saturation less than 90%)

near ATP2B4 · rs116133558

What the study found

Who was studied 10,759 Hispanic/Latino individuals.

The effect Each copy of the T allele shifted the measure 1.18 lower (95% confidence interval 0.81-1.55); p = 4 × 10−10.

Where it sits Chromosome 1, band 1q32.1 — between genes, 3.6 kb from ATP2B4.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Obstructive sleep apnea trait (percentage sleep with oxyhemoglobin saturation less than 90%) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Obstructive sleep apnea trait (percentage sleep with oxyhemoglobin saturation less than 90%).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Obstructive sleep apnea trait (percentage sleep with oxyhemoglobin saturation less than 90%) compared to the general population.
Source

Questions about rs116133558

What is rs116133558?

rs116133558 is a single position in the genome, in or near the near ATP2B4 gene. Published research associates it with obstructive sleep apnea trait (percentage sleep with oxyhemoglobin saturation less than 90%). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs116133558 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs116133558 come from?

GWAS Catalog, Genome medicine 2021, PMID:34446064. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Obstructive sleep apnea trait (percentage sleep with oxyhemoglobin saturation less than 90%) (rs116133558). MyGeneLog™. https://www.mygenelog.com/variants/rs116133558

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