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Systolic blood pressure

RAB5B · rs11611029

Where this position leads

Condition: Blood Pressure

rs11611029 Condition: Blood Pressure Blood Pressure Condition rs11611029 rs11611029 RAB5B

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0119 higher (95% confidence interval 0.0088-0.015); p = 2 × 10−14.

Where it sits Chromosome 12, band 12q13.2 — in an intron of RAB5B.

What each result means

C/C No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11611029

What is rs11611029?

rs11611029 is a single position in the genome, in or near the RAB5B gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11611029 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs11611029 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11611029 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs11611029). MyGeneLog™. https://www.mygenelog.com/variants/rs11611029

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