Standard

Body mass index

P2RX4 · rs11610621

Where this position leads

Condition: Childhood Body Mass Index

rs11610621 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs11610621 rs11610621 P2RX4

What the study found

Who was studied 650,000 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0174 lower (95% confidence interval 0.012-0.022); p = 2 × 10−11.

How common The T allele had a frequency of about 84% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of P2RX4.

What each result means

A/A No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11610621

What is rs11610621?

rs11610621 is a single position in the genome, in or near the P2RX4 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11610621 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs11610621 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11610621 come from?

GWAS Catalog, Nature genetics 2024, PMID:39375568. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs11610621). MyGeneLog™. https://www.mygenelog.com/variants/rs11610621

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