Interleukin-36 alpha level in Chronic kidney disease with hypertension and no diabetes (14150_7)
near FKBPL · rs116081888
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 466 African American individuals.
The effect
Each copy of the G allele shifted the measure 1.34 higher (95% confidence interval 1.07-1.61); p = 8 × 10−23.
How common The G allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 2.3 kb from FKBPL.
What each result means
C/CNo copy of the version the research linked to Interleukin-36 alpha level in Chronic kidney disease with hypertension and no diabetes (14150_7). This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Interleukin-36 alpha level in Chronic kidney disease with hypertension and no diabetes (14150_7). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Interleukin-36 alpha level in Chronic kidney disease with hypertension and no diabetes (14150_7). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs116081888 is a single position in the genome, in or near the near FKBPL gene. Published research associates it with interleukin-36 alpha level in chronic kidney disease with hypertension and no diabetes (14150_7). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs116081888 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116081888 come from?
GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Interleukin-36 alpha level in Chronic kidney disease with hypertension and no diabetes (14150_7) (rs116081888). MyGeneLog™. https://www.mygenelog.com/variants/rs116081888