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Intraocular pressure

PRSS23 · rs11606902

Where this position leads

Condition: Intraocular Pressure

rs11606902 Condition: Intraocular Pressure Intraocular Pressure Condition rs11606902 rs11606902 PRSS23

What the study found

Who was studied 139,555 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.098 lower (95% confidence interval 0.067-0.129); p = 6 × 10−10.

How common The C allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 11, band 11q14.2 — between genes, 1.9 kb from PRSS23.

What each result means

C/C Two copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
T/T No copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
Source

Questions about rs11606902

What is rs11606902?

rs11606902 is a single position in the genome, in or near the PRSS23 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11606902 linked to?

On MyGeneLog this position is linked to Intraocular Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs11606902 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11606902 come from?

GWAS Catalog, Nature genetics 2018, PMID:29785010. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Intraocular pressure (rs11606902). MyGeneLog™. https://www.mygenelog.com/variants/rs11606902

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