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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 95,827 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.22 higher (95% confidence interval 0.16-0.28); p = 8 × 10−13.
Where it sits Chromosome 2, band 2q31.2 — in an intron of AGPS.
What each result means
A/ATwo copies of the version the research linked to Spherical equivalent. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Spherical equivalent. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Spherical equivalent. This is the starting point the study compared everyone against.
rs116039674 is a single position in the genome, in or near the AGPS gene. Published research associates it with spherical equivalent. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs116039674 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116039674 come from?
GWAS Catalog, JAMA ophthalmology 2020, PMID:32352494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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