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Optic disc size

DCDC1 · rs11602582

What the study found

Who was studied 67,040 British ancestry individuals; replicated in 28,509 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.04 lower; p = 4 × 10−15.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 11, band 11p13 — in an intron of DCDC1.

What each result means

A/A Two copies of the version the research linked to Optic disc size. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Optic disc size. That is a smaller link than two copies.
G/G No copy of the version the research linked to Optic disc size. This is the starting point the study compared everyone against.
Source

Questions about rs11602582

What is rs11602582?

rs11602582 is a single position in the genome, in or near the DCDC1 gene. Published research associates it with optic disc size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11602582 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11602582 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:31809533. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Optic disc size (rs11602582). MyGeneLog™. https://www.mygenelog.com/variants/rs11602582

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