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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 342,387 European ancestry individuals, 6,017 African ancestry individuals, 7,325 South Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0214 lower (95% confidence interval 0.015-0.027); p = 1 × 10−11.
Where it sits Chromosome 11, band 11q21 — in an intron of SMCO4.
What each result means
C/CNo copy of the version the research linked to Alanine aminotransferase levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Alanine aminotransferase levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alanine aminotransferase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs11601368
What is rs11601368?
rs11601368 is a single position in the genome, in or near the SMCO4 gene. Published research associates it with alanine aminotransferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11601368 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11601368 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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