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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 7,751 European ancestry individuals; replicated in 1,005 European ancestry individuals, 3,669 Asian Indian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.04 U/L lower (95% confidence interval 0.025-0.053); p = 2 × 10−8.
How common The A allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 10, band 10q24.31 — between genes, 4.1 kb from CYP2C23P.
What each result means
A/ATwo copies of the version the research linked to Liver enzyme levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Liver enzyme levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Liver enzyme levels. This is the starting point the study compared everyone against.
American journal of human genetics · 2008 · PMID 18940312
Questions about rs11597390
What is rs11597390?
rs11597390 is a single position in the genome, in or near the CHUK gene. Published research associates it with liver enzyme levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11597390 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11597390 come from?
GWAS Catalog, Am J Hum Genet 2008, PMID:18940312. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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