Sensitive

Rheumatoid arthritis

near RBM17 · rs11594656

Where this position leads

Condition: Rheumatoid Arthritis

rs11594656 Condition: Rheumatoid Arthritis Rheumatoid Arthritis Condition rs11594656 rs11594656 near RBM17

What the study found

Who was studied 14,361 European ancestry cases, 43,923 European ancestry controls, 8,267 East Asian ancestry cases, 244,741 East Asian ancestry controls.

The effect Each copy of the A allele shifted the measure 0.1 lower (95% confidence interval 0.067-0.133); p = 4 × 10−9.

Where it sits Chromosome 10, band 10p15.1 — between genes, 6.9 kb from RBM17.

What each result means

A/A Two copies of the version the research linked to Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Rheumatoid arthritis. That is a smaller link than two copies.
T/T No copy of the version the research linked to Rheumatoid arthritis. This is the starting point the study compared everyone against.
Source

Questions about rs11594656

What is rs11594656?

rs11594656 is a single position in the genome, in or near the near RBM17 gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11594656 linked to?

On MyGeneLog this position is linked to Rheumatoid Arthritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs11594656 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11594656 come from?

GWAS Catalog, Annals of the rheumatic diseases 2021, PMID:33310728. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Rheumatoid arthritis (rs11594656). MyGeneLog™. https://www.mygenelog.com/variants/rs11594656

← See all variants