TCF7L2 · rs11594610
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 76,029 white-British ancestry individuals; replicated in 10,130 non white-British ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.0843 lower (95% confidence interval 0.062-0.107); p = 7 × 10−16.
How common The G allele had a frequency of about 80% in the people studied.
Where it sits Chromosome 10, band 10q25.3 — in an intron of TCF7L2.
rs11594610 is a single position in the genome, in or near the TCF7L2 gene. Published research associates it with corneal resistance factor. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Communications biology 2020, PMID:33311554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Corneal resistance factor (rs11594610). MyGeneLog™. https://www.mygenelog.com/variants/rs11594610