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FCGR2B protein levels

near FCGR2A · rs115944227

What the study found

Who was studied 497 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.791 higher (95% confidence interval 0.55-1.04); p = 6 × 10−10.

Where it sits Chromosome 1, band 1q23.3 — between genes, 11.3 kb from FCGR2A.

What each result means

A/A No copy of the version the research linked to FCGR2B protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to FCGR2B protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to FCGR2B protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs115944227

What is rs115944227?

rs115944227 is a single position in the genome, in or near the near FCGR2A gene. Published research associates it with fcgr2b protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs115944227 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs115944227 come from?

GWAS Catalog, Scientific reports 2024, PMID:38565889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

FCGR2B protein levels (rs115944227). MyGeneLog™. https://www.mygenelog.com/variants/rs115944227

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