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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 28,936 European ancestry individuals; replicated in 7,912 European ancestry individuals, 5,696 East Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.065 lower (95% confidence interval 0.049-0.082); p = 5 × 10−15.
How common The T allele had a frequency of about 45% in the people studied.
Where it sits Chromosome 17, band 17q24.3 — in an intron of ROCR.
What each result means
C/CNo copy of the version the research linked to Intertrochanteric region size. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Intertrochanteric region size. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Intertrochanteric region size. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 31053729 · open access
Questions about rs1159421
What is rs1159421?
rs1159421 is a single position in the genome, in or near the SOX9 gene. Published research associates it with intertrochanteric region size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1159421 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1159421 come from?
GWAS Catalog, Nature communications 2019, PMID:31053729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Intertrochanteric region size (rs1159421). MyGeneLog™. https://www.mygenelog.com/variants/rs1159421