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Male-pattern baldness

C10orf11 · rs11593840

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs11593840 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs11593840 rs11593840 C10orf11

What the study found

Who was studied 25,662 British ancestry cases, 17,928 British ancestry controls; replicated in 13,367 European ancestry cases, 11,851 European ancestry controls, 3,436 cases, 2,435 controls.

The effect Each copy of the A allele shifted the measure 0.142 lower (95% confidence interval 0.11-0.17); p = 9 × 10−24.

Where it sits Chromosome 10, band 10q22.3 — in an intron of LRMDA.

What each result means

A/A Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
G/G No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
Source

Questions about rs11593840

What is rs11593840?

rs11593840 is a single position in the genome, in or near the C10orf11 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11593840 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs11593840 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11593840 come from?

GWAS Catalog, Nat Commun 2017, PMID:29146897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs11593840). MyGeneLog™. https://www.mygenelog.com/variants/rs11593840

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