Standard
Acne (severe)
LOC643723 · rs1159268
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Acne (severe) compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Acne (severe).
G/G
Published research associates this genotype with typical/baseline likelihood of Acne (severe) — no copies of the reported risk allele.
Source
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris
Navarini AA,
Simpson MA,
Weale M,
Knight J,
Carlavan I,
Reiniche P,
Burden DA,
Layton A,
Bataille V,
Allen M,
Pleass R,
Pink A
and 11 more — show all
Creamer D,
English J,
Munn S,
Walton S,
Willis C,
Déret S,
Voegel JJ,
Spector T,
Smith CH,
Trembath RC,
Barker JN
Nature communications · 2014 · PMID 24927181
Questions about rs1159268
What is rs1159268?
rs1159268 is a single position in the genome, in or near the LOC643723 gene. Published research associates it with acne (severe). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1159268 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1159268 come from?
GWAS Catalog, Nat Commun 2014, PMID:24927181. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants