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Who was studied 119,715 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0432 SD higher (95% confidence interval 0.031-0.055); p = 7 × 10−13.
How common The G allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 10, band 10p14 — between genes, 18.5 kb from KRT8P37.
What each result means
C/CNo copy of the version the research linked to Thyroid stimulating hormone levels. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Thyroid stimulating hormone levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Thyroid stimulating hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2020 · PMID 32769997 · open access
Questions about rs11592436
What is rs11592436?
rs11592436 is a single position in the genome, in or near the LINC00708 gene. Published research associates it with thyroid stimulating hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11592436 linked to?
On MyGeneLog this position is linked to Thyroid Stimulating Hormone (TSH) Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs11592436 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11592436 come from?
GWAS Catalog, Nature communications 2020, PMID:32769997. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 12228Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others8Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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