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Paralytic ileus (PheCode 560.1)

MIR3976HG · rs115911656

What the study found

Who was studied 827 African American or Afro-Caribbean cases, 119,418 African American or Afro-Caribbean controls, 2,537 European ancestry cases, 442,939 European ancestry controls, 253 Hispanic or Latin American cases, 59,029 Hispanic or Latin American controls.

The effect Each copy of the A allele shifted the measure 2.5 lower (95% confidence interval 2.46-2.54); p = 4 × 10−11.

How common The A allele had a frequency of about 100% in the people studied.

Where it sits Chromosome 18, band 18p11.31 — in an intron of MIR3976HG.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Paralytic ileus (PheCode 560.1) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Paralytic ileus (PheCode 560.1).
G/G Published research associates this genotype with typical/baseline likelihood of Paralytic ileus (PheCode 560.1) — no copies of the reported risk allele.
Source

Questions about rs115911656

What is rs115911656?

rs115911656 is a single position in the genome, in or near the MIR3976HG gene. Published research associates it with paralytic ileus (phecode 560.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs115911656 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs115911656 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Paralytic ileus (PheCode 560.1) (rs115911656). MyGeneLog™. https://www.mygenelog.com/variants/rs115911656

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