1 15132117Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 3,655 European ancestry cases, 254,909 European ancestry controls.
The effect
Each copy of the A allele carried 1.61 times the odds of Fuchs's corneal dystrophy (95% confidence interval 1.427-1.81264); p = 7 × 10−15.
How common The A allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 1, band 1p32.3 — in an intron of SSBP3.
What each result means
A/ATwo copies of the version the research linked to Fuchs's corneal dystrophy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Fuchs's corneal dystrophy. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Fuchs's corneal dystrophy. This is the starting point the study compared everyone against.
Communications biology · 2024 · PMID 38582945 · open access
Questions about rs11590557
What is rs11590557?
rs11590557 is a single position in the genome, in or near the SSBP3 gene. Published research associates it with fuchs's corneal dystrophy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11590557 linked to?
On MyGeneLog this position is linked to Fuchs's Corneal Dystrophy. The research behind each link, and its sources, are set out on that condition page.
Does having rs11590557 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11590557 come from?
GWAS Catalog, Communications biology 2024, PMID:38582945. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 15132117Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.