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Sortilin levels (OLINK)

ATXN7L2 · rs11590351

What the study found

Who was studied 1,173 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 2 × 10−11.

How common The C allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 1, band 1p13.3 — in an intron of ATXN7L2.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Sortilin levels (OLINK) compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Sortilin levels (OLINK).
T/T Published research associates this genotype with typical/baseline likelihood of Sortilin levels (OLINK) — no copies of the reported risk allele.
Source

Questions about rs11590351

What is rs11590351?

rs11590351 is a single position in the genome, in or near the ATXN7L2 gene. Published research associates it with sortilin levels (olink). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11590351 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11590351 come from?

GWAS Catalog, Frontiers in cardiovascular medicine 2021, PMID:33937362. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sortilin levels (OLINK) (rs11590351). MyGeneLog™. https://www.mygenelog.com/variants/rs11590351

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