Sensitive

Autoimmune traits

EHMT2 · rs115884658

What the study found

Who was studied 1,383 Danish ancestry cases, 62,656 Danish ancestry controls.

The effect Each copy of the A allele carried 1.83 times the odds of Autoimmune traits (95% confidence interval 1.6-2.1); p = 2 × 10−15.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — a missense change in EHMT2.

What each result means

A/A Two copies of the version the research linked to Autoimmune traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Autoimmune traits. That is a smaller link than two copies.
G/G No copy of the version the research linked to Autoimmune traits. This is the starting point the study compared everyone against.
Source

Questions about rs115884658

What is rs115884658?

rs115884658 is a single position in the genome, in or near the EHMT2 gene. Published research associates it with autoimmune traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs115884658 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs115884658 come from?

GWAS Catalog, Brain, behavior, and immunity 2021, PMID:32534018. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Autoimmune traits (rs115884658). MyGeneLog™. https://www.mygenelog.com/variants/rs115884658

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