Sensitive

Haemorrhoidal disease

BMP8B · rs11585073

Where this position leads

Condition: Haemorrhoidal Disease

rs11585073 Condition: Haemorrhoidal Disease Haemorrhoidal Disease Condition rs11585073 rs11585073 BMP8B

What the study found

Who was studied 218,920 European ancestry cases, 725,213 European ancestry controls.

The effect Each copy of the A allele carried 1.06 times the odds of Haemorrhoidal disease (95% confidence interval 1.05-1.07); p = 4 × 10−33.

How common The A allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 1, band 1p34.2 — in a non-coding transcript of LINC02811.

What each result means

A/A Two copies of the version the research linked to Haemorrhoidal disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Haemorrhoidal disease. That is a smaller link than two copies.
T/T No copy of the version the research linked to Haemorrhoidal disease. This is the starting point the study compared everyone against.
Source

Questions about rs11585073

What is rs11585073?

rs11585073 is a single position in the genome, in or near the BMP8B gene. Published research associates it with haemorrhoidal disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11585073 linked to?

On MyGeneLog this position is linked to Haemorrhoidal Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs11585073 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11585073 come from?

GWAS Catalog, Gut 2021, PMID:33888516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Haemorrhoidal disease (rs11585073). MyGeneLog™. https://www.mygenelog.com/variants/rs11585073

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