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Who was studied 434 European ancestry cases with coronary artery disease, 3,123 European ancestry cases without coronary artery disease; replicated in 585 cases with coronary artery disease, 2,612 cases without coronary artery disease.
The effect
Each copy of the T allele carried 3.16 times the odds of Coronary artery disease in type 1 diabetes; p = 1 × 10−9.
How common The T allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 5, band 5q13.2 — in an intron of LOC105379028.
What each result means
C/CNo copy of the version the research linked to Coronary artery disease in type 1 diabetes. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Coronary artery disease in type 1 diabetes. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Coronary artery disease in type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Cardiovascular diabetology · 2018 · PMID 29695241 · open access
Questions about rs115829748
What is rs115829748?
rs115829748 is a single position in the genome, in or near the MAP1B gene. Published research associates it with coronary artery disease in type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs115829748 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs115829748 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115829748 come from?
GWAS Catalog, Cardiovasc Diabetol 2018, PMID:29695241. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Coronary artery disease in type 1 diabetes (rs115829748). MyGeneLog™. https://www.mygenelog.com/variants/rs115829748