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Ulcerative colitis

IL23R · rs11581607

Where this position leads

Condition: Ulcerative Colitis

rs11581607 Condition: Ulcerative Colitis Ulcerative Colitis Condition rs11581607 rs11581607 IL23R

What the study found

Who was studied 4,252 European ancestry cases, 311,416 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.368 higher (95% confidence interval 0.27-0.47); p = 2 × 10−12.

How common The G allele had a frequency of about 93% in the people studied.

Where it sits Chromosome 1, band 1p31.3 — in an intron of IL23R.

What each result means

A/A No copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11581607

What is rs11581607?

rs11581607 is a single position in the genome, in or near the IL23R gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11581607 linked to?

On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs11581607 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11581607 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ulcerative colitis (rs11581607). MyGeneLog™. https://www.mygenelog.com/variants/rs11581607

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