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Who was studied 3,037,499 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0146 higher (95% confidence interval 0.01-0.019); p = 4 × 10−11.
How common The T allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 1, band 1p34.2 — between genes, 5.2 kb from MPL.
What each result means
G/GPublished research associates this genotype with typical/baseline likelihood of Educational attainment — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Educational attainment.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Educational attainment compared to the general population.
Nature genetics · 2022 · PMID 35361970 · open access
Questions about rs11576614
What is rs11576614?
rs11576614 is a single position in the genome, in or near the near MPL gene. Published research associates it with educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11576614 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does having rs11576614 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11576614 come from?
GWAS Catalog, Nature genetics 2022, PMID:35361970. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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