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Platelet distribution width

SKI · rs11576356

What the study found

Who was studied 164,433 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0299 lower (95% confidence interval 0.021-0.039); p = 2 × 10−10.

How common The A allele had a frequency of about 18% in the people studied.

Where it sits Chromosome 1, band 1p36.32 — in an intron of SKI.

What each result means

A/A Two copies of the version the research linked to Platelet distribution width. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Platelet distribution width. That is a smaller link than two copies.
G/G No copy of the version the research linked to Platelet distribution width. This is the starting point the study compared everyone against.
Source

Questions about rs11576356

What is rs11576356?

rs11576356 is a single position in the genome, in or near the SKI gene. Published research associates it with platelet distribution width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11576356 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11576356 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet distribution width (rs11576356). MyGeneLog™. https://www.mygenelog.com/variants/rs11576356

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