0 433225223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI5Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,999 Han Chinese ancestry male individuals; replicated in 1,496 Han Chinese ancestry male individuals.
The effect
Each copy of the A allele shifted the measure 0.23 g/L lower (95% confidence interval 0.21-0.25); p = 1 × 10−54.
How common The A allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — a synonymous change in NCR3.
What each result means
A/ATwo copies of the version the research linked to Complement C3 and C4 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Complement C3 and C4 levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Complement C3 and C4 levels. This is the starting point the study compared everyone against.
PLoS genetics · 2012 · PMID 23028341 · open access
Questions about rs11575839
What is rs11575839?
rs11575839 is a single position in the genome, in or near the HLA-C gene. Published research associates it with complement c3 and c4 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11575839 linked to?
On MyGeneLog this position is linked to Complement C3 and C4 Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs11575839 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11575839 come from?
GWAS Catalog, PLoS Genet 2012, PMID:23028341. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 433225223222Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity2Meta AI5Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total43Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Complement C3 and C4 levels (rs11575839). MyGeneLog™. https://www.mygenelog.com/variants/rs11575839