Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP
PLA2G5 · rs11573260
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 6,692 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 1.8 higher (95% confidence interval 1.37-2.23); p = 3 × 10−18.
How common The T allele had a frequency of about 1% in the people studied.
Where it sits Chromosome 1, band 1p36.13 — in the 5′ untranslated region of PLA2G5.
What each result means
C/CNo copy of the version the research linked to Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP. That is the strongest link of the three results. A link in a study is not a diagnosis.
Arteriosclerosis, thrombosis, and vascular biology · 2019 · PMID 31070471
Questions about rs11573260
What is rs11573260?
rs11573260 is a single position in the genome, in or near the PLA2G5 gene. Published research associates it with group iia secretory phospholipase a2 levels in individuals with elevated hscrp. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11573260 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11573260 come from?
GWAS Catalog, Arteriosclerosis, thrombosis, and vascular biology 2019, PMID:31070471. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP (rs11573260). MyGeneLog™. https://www.mygenelog.com/variants/rs11573260