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Blood glucose levels

MYBPC3 · rs11570115

Where this position leads

Condition: Gout

rs11570115 Condition: Gout Gout Condition rs11570115 rs11570115 MYBPC3

What the study found

Who was studied 313,125 European ancestry individuals, 5,568 African ancestry individuals, 6,693 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0374 lower (95% confidence interval 0.029-0.046); p = 1 × 10−18.

Where it sits Chromosome 11, band 11p11.2 — in an intron of MYBPC3.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 5 submitters), last evaluated 2015-03-03. ClinVar record 188578 NM_000256.3(MYBPC3):c.3191-21A>G

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

C/C Two copies of the version the research linked to Blood glucose levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Blood glucose levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Blood glucose levels. This is the starting point the study compared everyone against.
Source

Questions about rs11570115

What is rs11570115?

rs11570115 is a single position in the genome, in or near the MYBPC3 gene. Published research associates it with blood glucose levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11570115 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs11570115 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11570115 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blood glucose levels (rs11570115). MyGeneLog™. https://www.mygenelog.com/variants/rs11570115

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