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Creatine kinase levels

CKM · rs11559024

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 63,159 Icelandic ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.446 lower; p = 2 × 10−115.

How common The C allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 19, band 19q13.32 — a missense change in CKM.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Creatine kinase levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Creatine kinase levels.
T/T Published research associates this genotype with typical/baseline likelihood of Creatine kinase levels — no copies of the reported risk allele.
Source
Common and rare variants associating with serum levels of creatine kinase and lactate dehydrogenase
Kristjansson RP, Oddsson A, Helgason H, Sveinbjornsson G, Arnadottir GA, Jensson BO, Jonasdottir A, Jonasdottir A, Bragi Walters G, Sulem G, Oskarsdottir A, Benonisdottir S
and 12 more — show all
Davidsson OB, Masson G, Magnusson OT, Holm H, Sigurdardottir O, Jonsdottir I, Eyjolfsson GI, Olafsson I, Gudbjartsson DF, Thorsteinsdottir U, Sulem P, Stefansson K
Nature communications · 2016 · PMID 26838040 · open access

Questions about rs11559024

What is rs11559024?

rs11559024 is a single position in the genome, in or near the CKM gene. Published research associates it with creatine kinase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11559024 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11559024 come from?

GWAS Catalog, Nature communications 2016, PMID:26838040. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatine kinase levels (rs11559024). MyGeneLog™. https://www.mygenelog.com/variants/rs11559024

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