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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,466 Black/admixed ancestry individuals; replicated in up to 1,653 European, Hispanic, Asian or Black individuals.
The effect
Each copy of the T allele shifted the measure 0.552 lower (95% confidence interval 0.46-0.64); p = 3 × 10−32.
Where it sits Chromosome 11, band 11q13.1 — in an intron of SLC25A45.
What each result means
C/CNo copy of the version the research linked to N6,n6,n6-trimethyllysine levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to N6,n6,n6-trimethyllysine levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to N6,n6,n6-trimethyllysine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35995766 · open access
Questions about rs115561468
What is rs115561468?
rs115561468 is a single position in the genome, in or near the SLC25A45 gene. Published research associates it with n6,n6,n6-trimethyllysine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs115561468 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115561468 come from?
GWAS Catalog, Nature communications 2022, PMID:35995766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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