A/APublished research associates this genotype with typical/baseline likelihood of Alzheimer's disease (late onset) — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Alzheimer's disease (late onset).
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Alzheimer's disease (late onset) compared to the general population.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs115550680
What is rs115550680?
rs115550680 is a single position in the genome, in or near the ABCA7 gene. Published research associates it with alzheimer's disease (late onset). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs115550680 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs115550680?
Subjects that appear in the title or abstract of the same papers as this rsID include brain and memory (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs115550680 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115550680 come from?
GWAS Catalog, JAMA 2013, PMID:23571587. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.