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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 14,296 European ancestry individuals; replicated in 5,698 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.177 higher (95% confidence interval 0.13-0.22); p = 5 × 10−14.
How common The T allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 2, band 2p25.3 — a synonymous change in ACP1.
What each result means
C/CNo copy of the version the research linked to Glycerate levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Glycerate levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Glycerate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature medicine · 2022 · PMID 36357675 · open access
Questions about rs11553742
What is rs11553742?
rs11553742 is a single position in the genome, in or near the ACP1 gene. Published research associates it with glycerate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11553742 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11553742 come from?
GWAS Catalog, Nature medicine 2022, PMID:36357675. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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