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Serum levels of protein TXNDC5

OGFOD3 · rs11546697

What the study found

Who was studied 5,362 Icelandic ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.232 higher (95% confidence interval 0.2-0.27); p = 2 × 10−38.

How common The G allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 17, band 17q25.3 — in the 3′ untranslated region of OGFOD3.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Serum levels of protein TXNDC5 — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serum levels of protein TXNDC5.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serum levels of protein TXNDC5 compared to the general population.
Source

Questions about rs11546697

What is rs11546697?

rs11546697 is a single position in the genome, in or near the OGFOD3 gene. Published research associates it with serum levels of protein txndc5. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11546697 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11546697 come from?

GWAS Catalog, Nature communications 2022, PMID:35078996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum levels of protein TXNDC5 (rs11546697). MyGeneLog™. https://www.mygenelog.com/variants/rs11546697

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