CHRM3 · rs115455482
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 91 European ancestry cases, 220 African American cases, 1,826 European ancestry controls, 2,148 African American controls; replicated in 256 European ancestry cases, 142 African American cases, 2,118 European ancestry controls, 1,114 African American controls.
The effect Each copy of the T allele shifted the measure 0.11 higher; p = 6 × 10−11.
How common The T allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 1, band 1q43 — in an intron of CHRM3.
rs115455482 is a single position in the genome, in or near the CHRM3 gene. Published research associates it with hallucinations in long-term cannabis use. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Translational psychiatry 2019, PMID:31740666. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hallucinations in long-term cannabis use (rs115455482). MyGeneLog™. https://www.mygenelog.com/variants/rs115455482