GPER1 · rs11544331
Where this position leads
Condition: Prostate Cancer
What the study found
Who was studied 985 Korean ancestry cases and 6,273 Korean ancestry controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−15.
How common The T allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 7, band 7p22.3 — a missense change in GPER1.
What ClinVar records
Classification
Benign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2020-04-28.
ClinVar record 1248609 NM_001098201.3(GPER1):c.47C>T (p.Pro16Leu)
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs11544331 is a single position in the genome, in or near the GPER1 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Scientific reports 2019, PMID:31748686. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Prostate cancer (rs11544331). MyGeneLog™. https://www.mygenelog.com/variants/rs11544331