0 211142229Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot4Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others9Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 857 African American or Afro-Caribbean cases, 119,909 African American or Afro-Caribbean controls, 5,229 European ancestry cases, 442,102 European ancestry controls, 529 Hispanic or Latin American cases, 58,892 Hispanic or Latin American controls.
The effect
Each copy of the C allele shifted the measure 0.921 lower (95% confidence interval 0.88-0.96); p = 7 × 10−53.
How common The C allele had a frequency of about 99% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — in an intron of TSBP1.
What each result means
C/CTwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs115378818
What is rs115378818?
rs115378818 is a single position in the genome, in or near the TSBP1 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs115378818 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs115378818 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115378818 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 211142229Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot4Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others9Total21Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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