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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,087 Sub-Saharan African ancestry individuals; replicated in 4,874 African American individuals.
The effect
Each copy of the T allele shifted the measure 0.778 lower (95% confidence interval 0.52-1.03); p = 4 × 10−9.
Where it sits Chromosome 5, band 5q32 — in an intron of JAKMIP2.
What each result means
C/CNo copy of the version the research linked to Insulin levels in overweight individuals. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Insulin levels in overweight individuals. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Insulin levels in overweight individuals. That is the strongest link of the three results. A link in a study is not a diagnosis.
Genome medicine · 2021 · PMID 34620218 · open access
Questions about rs115318065
What is rs115318065?
rs115318065 is a single position in the genome, in or near the JAKMIP2 gene. Published research associates it with insulin levels in overweight individuals. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs115318065 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115318065 come from?
GWAS Catalog, Genome medicine 2021, PMID:34620218. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Insulin levels in overweight individuals (rs115318065). MyGeneLog™. https://www.mygenelog.com/variants/rs115318065