0 202123210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity2Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 523,783 European ancestry individuals; replicated in 59,206 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0259 higher (95% confidence interval 0.017-0.035); p = 7 × 10−9.
How common The C allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 6, band 6p22.1 — between genes, 8.3 kb from CDCA7P1.
What each result means
C/CTwo copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
rs115091345 is a single position in the genome, in or near the near POM121L2 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs115091345 linked to?
On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.
Does having rs115091345 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115091345 come from?
GWAS Catalog, Nat Genet 2019, PMID:30643256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 202123210Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity2Meta AI0Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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