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SLAMF7 protein levels

SLAMF7 · rs115018834

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.147 higher (95% confidence interval 0.11-0.18); p = 4 × 10−20.

How common The C allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 1, band 1q23.3 — in an intron of SLAMF7.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of SLAMF7 protein levels compared to the general population.
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with SLAMF7 protein levels.
G/G Published research associates this genotype with typical/baseline likelihood of SLAMF7 protein levels — no copies of the reported risk allele.
Source

Questions about rs115018834

What is rs115018834?

rs115018834 is a single position in the genome, in or near the SLAMF7 gene. Published research associates it with slamf7 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs115018834 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs115018834 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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SLAMF7 protein levels (rs115018834). MyGeneLog™. https://www.mygenelog.com/variants/rs115018834

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