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Medication use (adrenergics, inhalants)

AC004041.2 · rs115008099

Where this position leads

Condition: Medication Use as a Genetic Trait

rs115008099 Condition: Medication Use as a Genetic Trait Medication Use as a Genetic Trait Condition rs115008099 rs115008099 AC004041.2

What the study found

Who was studied 28,880 European ancestry cases, 147,565 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.106 higher (95% confidence interval 0.081-0.13); p = 1 × 10−17.

How common The T allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 5, band 5q31.1 — in an intron of TH2LCRR.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Medication use (adrenergics, inhalants) — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Medication use (adrenergics, inhalants).
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Medication use (adrenergics, inhalants) compared to the general population.
Source

Questions about rs115008099

What is rs115008099?

rs115008099 is a single position in the genome, in or near the AC004041.2 gene. Published research associates it with medication use (adrenergics, inhalants). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs115008099 linked to?

On MyGeneLog this position is linked to Medication Use as a Genetic Trait. The research behind each link, and its sources, are set out on that condition page.

Does having rs115008099 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs115008099 come from?

GWAS Catalog, Nat Commun 2019, PMID:31015401. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Medication use (adrenergics, inhalants) (rs115008099). MyGeneLog™. https://www.mygenelog.com/variants/rs115008099

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