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Platelet count

DNM3 · rs11497367

What the study found

Who was studied 408,112 British individuals.

The effect Each copy of the A allele shifted the measure 0.0471 lower (95% confidence interval 0.036-0.058); p = 5 × 10−17.

How common The A allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 1, band 1q24.3 — in an intron of DNM3.

What each result means

A/A Two copies of the version the research linked to Platelet count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Platelet count. That is a smaller link than two copies.
G/G No copy of the version the research linked to Platelet count. This is the starting point the study compared everyone against.
Source

Questions about rs11497367

What is rs11497367?

rs11497367 is a single position in the genome, in or near the DNM3 gene. Published research associates it with platelet count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11497367 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11497367 come from?

GWAS Catalog, Cell 2020, PMID:32888494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet count (rs11497367). MyGeneLog™. https://www.mygenelog.com/variants/rs11497367

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