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Cognitive aspects of educational attainment

EXOC4 · rs1149557

Where this position leads

Condition: Educational Attainment

rs1149557 Condition: Educational Attainment Educational Attainment Condition rs1149557 rs1149557 EXOC4

What the study found

Who was studied 257,700 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0433 higher (95% confidence interval 0.031-0.056); p = 2 × 10−11.

How common The C allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 7, band 7q33 — in an intron of EXOC4.

What each result means

C/C Two copies of the version the research linked to Cognitive aspects of educational attainment. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Cognitive aspects of educational attainment. That is a smaller link than two copies.
T/T No copy of the version the research linked to Cognitive aspects of educational attainment. This is the starting point the study compared everyone against.
Source

Questions about rs1149557

What is rs1149557?

rs1149557 is a single position in the genome, in or near the EXOC4 gene. Published research associates it with cognitive aspects of educational attainment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1149557 linked to?

On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.

Does having rs1149557 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1149557 come from?

GWAS Catalog, Nature genetics 2021, PMID:33414549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cognitive aspects of educational attainment (rs1149557). MyGeneLog™. https://www.mygenelog.com/variants/rs1149557

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