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High density lipoprotein cholesterol levels

near BEAN1 · rs114876144

What the study found

Who was studied 99,432 Admixed African or African ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0708 higher (95% confidence interval 0.051-0.091); p = 1 × 10−11.

How common The G allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 16, band 16q21 — between genes, 7.3 kb from BEAN1.

What each result means

G/G Two copies of the version the research linked to High density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to High density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to High density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs114876144

What is rs114876144?

rs114876144 is a single position in the genome, in or near the near BEAN1 gene. Published research associates it with high density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs114876144 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114876144 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High density lipoprotein cholesterol levels (rs114876144). MyGeneLog™. https://www.mygenelog.com/variants/rs114876144

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