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Merkel cell polyomavirus VP1 antibody levels

OR2E1P · rs114708114

What the study found

Who was studied 5,915 White British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.37 higher (95% confidence interval 0.24-0.50); p = 2 × 10−8.

How common The C allele had a frequency of about 98% in the people studied.

Where it sits Chromosome 6, band 6p22.1 — between genes, 2.3 kb from OR2E1P.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Merkel cell polyomavirus VP1 antibody levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Merkel cell polyomavirus VP1 antibody levels.
T/T Published research associates this genotype with typical/baseline likelihood of Merkel cell polyomavirus VP1 antibody levels — no copies of the reported risk allele.
Source

Questions about rs114708114

What is rs114708114?

rs114708114 is a single position in the genome, in or near the OR2E1P gene. Published research associates it with merkel cell polyomavirus vp1 antibody levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs114708114 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114708114 come from?

GWAS Catalog, Open Forum Infect Dis 2020, PMID:33204752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Merkel cell polyomavirus VP1 antibody levels (rs114708114). MyGeneLog™. https://www.mygenelog.com/variants/rs114708114

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