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Eosinophil side fluorescence

TMEM131 · rs114673995

What the study found

Who was studied 30,531 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.217 SD units lower (95% confidence interval 0.16-0.27); p = 2 × 10−15.

How common The A allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 2, band 2q11.2 — in an intron of TMEM131.

What each result means

A/A Two copies of the version the research linked to Eosinophil side fluorescence. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Eosinophil side fluorescence. That is a smaller link than two copies.
G/G No copy of the version the research linked to Eosinophil side fluorescence. This is the starting point the study compared everyone against.
Source

Questions about rs114673995

What is rs114673995?

rs114673995 is a single position in the genome, in or near the TMEM131 gene. Published research associates it with eosinophil side fluorescence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs114673995 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114673995 come from?

GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Eosinophil side fluorescence (rs114673995). MyGeneLog™. https://www.mygenelog.com/variants/rs114673995

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