Standard

ICD10 D25: Leiomyoma of uterus

LINC01618 · rs114672778

Where this position leads

Condition: Uterine Fibroids

rs114672778 Condition: Uterine Fibroids Uterine Fibroids Condition rs114672778 rs114672778 LINC01618

What the study found

Who was studied 51,378 European ancestry cases, 243,913 European ancestry controls.

The effect Each copy of the G allele carried 0.42 times the odds of ICD10 D25: Leiomyoma of uterus (95% confidence interval 0.35-0.51); p = 2 × 10−18.

Where it sits Chromosome 4, band 4q12 — in an intron of LINC01618.

What each result means

G/G Two copies of the version the research linked to ICD10 D25: Leiomyoma of uterus. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to ICD10 D25: Leiomyoma of uterus. That is a smaller link than two copies.
T/T No copy of the version the research linked to ICD10 D25: Leiomyoma of uterus. This is the starting point the study compared everyone against.
Source

Questions about rs114672778

What is rs114672778?

rs114672778 is a single position in the genome, in or near the LINC01618 gene. Published research associates it with icd10 d25: leiomyoma of uterus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs114672778 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs114672778 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114672778 come from?

GWAS Catalog, Nature medicine 2025, PMID:40069456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

ICD10 D25: Leiomyoma of uterus (rs114672778). MyGeneLog™. https://www.mygenelog.com/variants/rs114672778

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