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IL18R1 protein levels

IL18R1 · rs11465597

What the study found

Who was studied 489 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.609 lower (95% confidence interval 0.44-0.78); p = 1 × 10−11.

Where it sits Chromosome 2, band 2q12.1 — in an intron of IL18R1.

What each result means

A/A No copy of the version the research linked to IL18R1 protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to IL18R1 protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to IL18R1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11465597

What is rs11465597?

rs11465597 is a single position in the genome, in or near the IL18R1 gene. Published research associates it with il18r1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11465597 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11465597 come from?

GWAS Catalog, Scientific reports 2024, PMID:38565889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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IL18R1 protein levels (rs11465597). MyGeneLog™. https://www.mygenelog.com/variants/rs11465597

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