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Central nucleus volume

LINC02428 · rs114601774

What the study found

Who was studied 35,292 European ancestry individuals, 227 African ancestry individuals, 380 South Asian ancestry individuals, 115 East Asian ancestry individuals, 338 individuals.

The effect Each copy of the C allele shifted the measure 2.63 higher (95% confidence interval 1.84-3.41); p = 6 × 10−11.

Where it sits Chromosome 4, band 4q24 — in an intron of LINC02428.

What each result means

C/C Two copies of the version the research linked to Central nucleus volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Central nucleus volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Central nucleus volume. This is the starting point the study compared everyone against.
Source

Questions about rs114601774

What is rs114601774?

rs114601774 is a single position in the genome, in or near the LINC02428 gene. Published research associates it with central nucleus volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs114601774 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114601774 come from?

GWAS Catalog, Biological psychiatry 2024, PMID:37391117. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Central nucleus volume (rs114601774). MyGeneLog™. https://www.mygenelog.com/variants/rs114601774

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