IGFBP7 · rs114518130
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 295 European, African American, Asian, Native American and other admixed ancestry infants, 17 European, African American, Asian, Native American and other admixed ancestry sibling pairs, 116 European, African American, Asian, Native American and other admixed ancestry twin pairs..
The effect Each copy of the G allele shifted the measure 6.13 percent higher (95% confidence interval -); p = 4 × 10−10.
Where it sits Chromosome 4, band 4q12 — in an intron of IGFBP7.
rs114518130 is a single position in the genome, in or near the IGFBP7 gene. Published research associates it with brain volume in infants (grey matter). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Transl Psychiatry 2017, PMID:28763065. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.